95 Results for "

 Cimicifuga foetida Linn.

" in MedChemExpress (MCE) Product Catalog:
Products (95)

95 Results for " Cimicifuga foetida Linn." in MCE Product Catalog:

53
Silvestrol
Silvestrol
0 Images
53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Category:  

Agave americana Linn. Natural Products Agavaceae Plants Disease Research Fields Cancer

Target:  

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
14
Morusin
Morusin
0 Images
14 Cited Publications
Cat. No.: HY-N0622
CAS No.: 62596-29-6
Synonyms: Mulberrochromene
Category:  

Infection other families Flavonoids Anti-aging Flavones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB STAT Bacterial

Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
12
Vitexin
Vitexin
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12 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Category:  

Cardiovascular Disease Neurological Disease Anti-aging Flavones Metabolic Disease Plants Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Trigonella foenum-graecum Linn. Cancer

Target:  

Autophagy

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
10
Isobavachalcone
Isobavachalcone
0 Images
10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Purity:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
4
Asparagusic acid
Asparagusic acid
0 Images
4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Category:  

Infection Liliaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Asparagus officinalis L.

Target:  

Parasite Endogenous Metabolite

Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
2
Methyl vanillate
Methyl vanillate
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2 Cited Publications
Cat. No.: HY-75342
CAS No.: 3943-74-6
Category:  

Microorganisms Monophenols Oryza sativa Linn. Gramineae Phenols Plants

Target:  

Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite

Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
2
Moracin O
Moracin O
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2 Cited Publications
Cat. No.: HY-N3244
CAS No.: 123702-97-6
Category:  

Neurological Disease Phenols Polyphenols Plants Moraceae Disease Research Fields Inflammation/Immunology Morus alba Linn.

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS)

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects .
1
Cimifugin
Cimifugin
0 Images
1 Cited Publications
Cat. No.: HY-N0634
CAS No.: 37921-38-3
Synonyms: Cimitin
Category:  

Ranunculaceae Coumarins Phenylpropanoids Plants Cimicifuga racemosa (L.) Nutt. Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions . Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS .
1
Arnidiol
Arnidiol
0 Images
1 Cited Publications
Cat. No.: HY-N4165
CAS No.: 6750-30-7
Category:  

Triterpenes Terpenoids Dendranthema morifolium (Ramat.) Tzvel. Other Diseases Plants Compositae Disease Research Fields

Target:  

Others

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
1
Cimigenol
Cimigenol
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1 Cited Publications
Cat. No.: HY-N6988
CAS No.: 3779-59-7
Category:  

Triterpenes Terpenoids Ranunculaceae Plants  Cimicifuga foetida Linn. Disease Research Fields Cancer

Target:  

Others

Cimigenol is an active compound isolated from Cimicifuga, with potent anti-tumor activity .
1
3-Epioleanolic acid
3-Epioleanolic acid
0 Images
1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
1
Vitexin (Standard)
Vitexin (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-N0013R
CAS No.: 3681-93-4
Category:  

Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Trigonella foenum-graecum Linn.

Target:  

Reference Standards Autophagy

Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
Protodioscin
Protodioscin
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Cat. No.: HY-N0799
CAS No.: 55056-80-9
Category:  

Leguminosae Plants Endogenous metabolite Disease Research Fields Trigonella foenum-graecum Linn. Cancer Steroids

Target:  

Endogenous Metabolite

Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
Dalbergin
Dalbergin
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Cat. No.: HY-N8347
CAS No.: 482-83-7
Category:  

Dalbergia odorifera T. Chen Monophenols Leguminosae Other Diseases Coumarins Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

Apoptosis

Dalbergin is a composition of the extract from the Dalbergia Sissoo Linn. knot wood. Dalbergin demonstrats notable antioxidant ability .
Actein
Actein
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Cat. No.: HY-N6872
CAS No.: 18642-44-9
Category:  

Triterpenes Terpenoids Ranunculaceae Plants  Cimicifuga foetida Linn. Disease Research Fields Cancer

Target:  

JNK Akt Apoptosis Autophagy Reactive Oxygen Species (ROS)

Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
Cimiracemoside C
Cimiracemoside C
0 Images
Cat. No.: HY-N6971
CAS No.: 256925-92-5
Synonyms: Cimicifugoside M
Category:  

Triterpenes Terpenoids Ranunculaceae Metabolic Disease Plants  Cimicifuga foetida Linn. Disease Research Fields

Target:  

AMPK

Cimiracemoside C is an active component of Cimicifuga racemosa, activates AMPK, has the potential activity against diabetes .
Obtusin
Obtusin
0 Images
Cat. No.: HY-N6057
CAS No.: 70588-05-5
Category:  

Seeds of Cassia tora Linn. Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Plants

Target:  

Monoamine Oxidase

Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression .
Cimicifugoside H-1
Cimicifugoside H-1
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Cat. No.: HY-N9331
CAS No.: 163046-73-9
Synonyms: Cimicidanol-3-O-β-d-xyloside
Category:  

Triterpenes Terpenoids Ranunculaceae Metabolic Disease Plants  Cimicifuga foetida Linn. Disease Research Fields

Target:  

Others

Cimicifugoside H-1, a cyclolanostanol xyloside, is a major constituent of C. foetida L. extract. Cimicifugoside H-1 inhibits bone resorption and ovariectomy-induced bone loss .
Oxysophoridine
Oxysophoridine
0 Images
Cat. No.: HY-N1402
CAS No.: 54809-74-4
Synonyms: Sophoridine N-oxide
Category:  

Alkaloids other families Pyridine Alkaloids Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis

Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .
Assay Types